<?xml version="1.0" encoding="UTF-8"?>
<rdf:RDF
 xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
 xmlns:owl="http://www.w3.org/2002/07/owl#"
 xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
 xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
<owl:Ontology rdf:about="">
 <owl:imports rdf:resource="http://www.biopax.org/release/biopax-level3.owl#" />
</owl:Ontology>

<bp:TemplateReaction rdf:about="ef6b6565-adeb-4ab2-9548-c5dce7162105">
 <bp:product rdf:resource="3b1ee23d-13e6-4f3d-ab75-81f5a10527c5" />
 <bp:participant rdf:resource="3b1ee23d-13e6-4f3d-ab75-81f5a10527c5" />
</bp:TemplateReaction>

<bp:Control rdf:about="effefbfe-51b9-4b36-8f67-a9c671933e8d">
 <bp:controlled rdf:resource="9c194cd6-be95-4300-828f-906c7010adb6" />
 <bp:controller rdf:resource="3b1ee23d-13e6-4f3d-ab75-81f5a10527c5" />
 <bp:controlType rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">ACTIVATION</bp:controlType>
</bp:Control>

<bp:RelationshipXref rdf:about="0061e952-df94-447b-9f96-1e9023951c45">
 <bp:id rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">4780</bp:id>
 <bp:db rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">NCBI Gene</bp:db>
</bp:RelationshipXref>

<bp:PublicationXref rdf:about="01d10742-e8fb-4fa4-a179-cbebc9bd37d4">
 <bp:id rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">31992855</bp:id>
 <bp:db rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">pmid</bp:db>
</bp:PublicationXref>

<bp:Pathway rdf:about="2606ed15-9aff-4227-87b1-8b207d5998b8">
 <bp:pathwayComponent rdf:resource="9c194cd6-be95-4300-828f-906c7010adb6" />
 <bp:pathwayComponent rdf:resource="ef6b6565-adeb-4ab2-9548-c5dce7162105" />
 <bp:pathwayComponent rdf:resource="a9ee4253-ffe4-43f8-be86-990a1b6e75a0" />
 <bp:pathwayComponent rdf:resource="95dbda8d-df15-4f0b-8a33-0a4f5de667e4" />
 <bp:pathwayComponent rdf:resource="effefbfe-51b9-4b36-8f67-a9c671933e8d" />
 <bp:pathwayComponent rdf:resource="9f1e94e6-4341-4a37-94e7-f2ae060a33db" />
 <bp:pathwayComponent rdf:resource="75f0d103-c063-4b19-937a-4b0268118a1c" />
 <bp:pathwayComponent rdf:resource="dece396b-3aba-4e24-8029-7a416a784787" />
 <bp:pathwayComponent rdf:resource="be2ad5c9-bf2c-4569-84e1-793d88aaef8c" />
 <bp:pathwayComponent rdf:resource="0e381c47-57d9-4b6f-8940-0b80fa0f4194" />
 <bp:xref rdf:resource="2136d79d-7125-4aa4-92b8-caf44000b740" />
 <bp:xref rdf:resource="01d10742-e8fb-4fa4-a179-cbebc9bd37d4" />
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">NF-κB-p62-NRF2 survival signaling is associated with high ROR1 expression in chronic lymphocytic leukemia.</bp:displayName>
</bp:Pathway>

<bp:BioSource rdf:about="0a1b273b-6845-4843-abfa-d07b1277b2a8">
 <bp:xref rdf:resource="e21b8a18-5887-472e-80b6-03c0fccbf90a" />
</bp:BioSource>

<bp:UnificationXref rdf:about="2136d79d-7125-4aa4-92b8-caf44000b740">
 <bp:id rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">999205de-8768-483b-9203-6a775f533099</bp:id>
 <bp:db rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">BioFactoid</bp:db>
</bp:UnificationXref>

<bp:Control rdf:about="9c194cd6-be95-4300-828f-906c7010adb6">
 <bp:controller rdf:resource="a170583d-4fea-4cfc-8dd2-52446087573f" />
 <bp:controlType rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">ACTIVATION</bp:controlType>
</bp:Control>

<bp:RelationshipXref rdf:about="2cf0220f-1b11-4fef-a31e-2838df743a09">
 <bp:id rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">23636</bp:id>
 <bp:db rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">NCBI Gene</bp:db>
</bp:RelationshipXref>

<bp:TemplateReactionRegulation rdf:about="a9ee4253-ffe4-43f8-be86-990a1b6e75a0">
 <bp:controlled rdf:resource="be2ad5c9-bf2c-4569-84e1-793d88aaef8c" />
 <bp:controller rdf:resource="a170583d-4fea-4cfc-8dd2-52446087573f" />
 <bp:controlType rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">ACTIVATION</bp:controlType>
</bp:TemplateReactionRegulation>

<bp:RelationshipXref rdf:about="986e45b3-c9dd-4129-86b3-e902ef7485a0">
 <bp:id rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">4919</bp:id>
 <bp:db rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">NCBI Gene</bp:db>
</bp:RelationshipXref>

<bp:ProteinReference rdf:about="1ebbe45a-1207-435c-a38e-251a92e2dda9">
 <bp:xref rdf:resource="4aff273e-fb74-4983-99f9-13b3601f87eb" />
 <bp:organism rdf:resource="0a1b273b-6845-4843-abfa-d07b1277b2a8" />
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">NQO1</bp:displayName>
</bp:ProteinReference>

<bp:Protein rdf:about="6305e6e5-6154-4cde-be72-2d148b163eb7">
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">NF-kB</bp:displayName>
 <bp:entityReference rdf:resource="4f4d5a54-426c-46cb-ab59-e626976f1c05" />
</bp:Protein>

<bp:RelationshipXref rdf:about="ecfa8b51-2322-4021-bbd2-5d5f2df32eb5">
 <bp:id rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">93113</bp:id>
 <bp:db rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">ChEBI</bp:db>
</bp:RelationshipXref>

<bp:Interaction rdf:about="0e381c47-57d9-4b6f-8940-0b80fa0f4194">
 <bp:participant rdf:resource="ba1ea57f-b7c0-4359-919a-03391c3c03a6" />
 <bp:participant rdf:resource="6305e6e5-6154-4cde-be72-2d148b163eb7" />
</bp:Interaction>

<bp:TemplateReactionRegulation rdf:about="95dbda8d-df15-4f0b-8a33-0a4f5de667e4">
 <bp:controlled rdf:resource="ef6b6565-adeb-4ab2-9548-c5dce7162105" />
 <bp:controller rdf:resource="6305e6e5-6154-4cde-be72-2d148b163eb7" />
 <bp:controlType rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">ACTIVATION</bp:controlType>
</bp:TemplateReactionRegulation>

<bp:ProteinReference rdf:about="b3119976-2ea6-4174-a4f8-d0a135439612">
 <bp:xref rdf:resource="0061e952-df94-447b-9f96-1e9023951c45" />
 <bp:organism rdf:resource="0a1b273b-6845-4843-abfa-d07b1277b2a8" />
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">NRF2</bp:displayName>
</bp:ProteinReference>

<bp:Protein rdf:about="a170583d-4fea-4cfc-8dd2-52446087573f">
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">NRF2</bp:displayName>
 <bp:entityReference rdf:resource="b3119976-2ea6-4174-a4f8-d0a135439612" />
</bp:Protein>

<bp:ProteinReference rdf:about="4f4d5a54-426c-46cb-ab59-e626976f1c05">
 <bp:xref rdf:resource="3fc6b67b-45e8-4ce8-b0a6-d2e2ab023f00" />
 <bp:organism rdf:resource="0a1b273b-6845-4843-abfa-d07b1277b2a8" />
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">NF-kB</bp:displayName>
</bp:ProteinReference>

<bp:RelationshipXref rdf:about="ea070715-a49e-4994-88a7-f4f373e85d1c">
 <bp:id rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">9220</bp:id>
 <bp:db rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">ChEBI</bp:db>
</bp:RelationshipXref>

<bp:RelationshipXref rdf:about="4aff273e-fb74-4983-99f9-13b3601f87eb">
 <bp:id rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">1728</bp:id>
 <bp:db rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">NCBI Gene</bp:db>
</bp:RelationshipXref>

<bp:Interaction rdf:about="dece396b-3aba-4e24-8029-7a416a784787">
 <bp:participant rdf:resource="ba1ea57f-b7c0-4359-919a-03391c3c03a6" />
 <bp:participant rdf:resource="57f08854-e654-48ed-afe2-2e8fcf64f344" />
</bp:Interaction>

<bp:ProteinReference rdf:about="b4aa797e-4fc1-4119-8150-b16ed79d0f18">
 <bp:xref rdf:resource="986e45b3-c9dd-4129-86b3-e902ef7485a0" />
 <bp:organism rdf:resource="0a1b273b-6845-4843-abfa-d07b1277b2a8" />
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">ROR1 </bp:displayName>
</bp:ProteinReference>

<bp:Protein rdf:about="ba1ea57f-b7c0-4359-919a-03391c3c03a6">
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">ROR1 </bp:displayName>
 <bp:entityReference rdf:resource="b4aa797e-4fc1-4119-8150-b16ed79d0f18" />
</bp:Protein>

<bp:ProteinReference rdf:about="9a37090d-7a3f-4f5b-8ebf-60363ede8f2a">
 <bp:xref rdf:resource="2cf0220f-1b11-4fef-a31e-2838df743a09" />
 <bp:organism rdf:resource="0a1b273b-6845-4843-abfa-d07b1277b2a8" />
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">p62</bp:displayName>
</bp:ProteinReference>

<bp:Catalysis rdf:about="9f1e94e6-4341-4a37-94e7-f2ae060a33db">
 <bp:controller rdf:resource="6305e6e5-6154-4cde-be72-2d148b163eb7" />
 <bp:controlType rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">ACTIVATION</bp:controlType>
</bp:Catalysis>

<bp:Modulation rdf:about="75f0d103-c063-4b19-937a-4b0268118a1c">
 <bp:controlled rdf:resource="9f1e94e6-4341-4a37-94e7-f2ae060a33db" />
 <bp:controller rdf:resource="934a05dd-69b3-4974-ab68-ec1806d00d44" />
 <bp:controlType rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">INHIBITION</bp:controlType>
</bp:Modulation>

<bp:SmallMoleculeReference rdf:about="6c01247e-d58b-4f3e-99ed-5a10607cfd5c">
 <bp:xref rdf:resource="ea070715-a49e-4994-88a7-f4f373e85d1c" />
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">Cirmtuzumab</bp:displayName>
</bp:SmallMoleculeReference>

<bp:SmallMoleculeReference rdf:about="fadd0b61-0e6f-46da-9199-a524b154d424">
 <bp:xref rdf:resource="ecfa8b51-2322-4021-bbd2-5d5f2df32eb5" />
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">BMS-345541</bp:displayName>
</bp:SmallMoleculeReference>

<bp:RelationshipXref rdf:about="3fc6b67b-45e8-4ce8-b0a6-d2e2ab023f00">
 <bp:id rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">4790</bp:id>
 <bp:db rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">NCBI Gene</bp:db>
</bp:RelationshipXref>

<bp:SmallMolecule rdf:about="934a05dd-69b3-4974-ab68-ec1806d00d44">
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">BMS-345541</bp:displayName>
 <bp:entityReference rdf:resource="fadd0b61-0e6f-46da-9199-a524b154d424" />
</bp:SmallMolecule>

<bp:Protein rdf:about="3b1ee23d-13e6-4f3d-ab75-81f5a10527c5">
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">p62</bp:displayName>
 <bp:entityReference rdf:resource="9a37090d-7a3f-4f5b-8ebf-60363ede8f2a" />
</bp:Protein>

<bp:TemplateReaction rdf:about="be2ad5c9-bf2c-4569-84e1-793d88aaef8c">
 <bp:product rdf:resource="7de0a2db-bd76-4bfa-8368-034f9e6657ec" />
 <bp:participant rdf:resource="7de0a2db-bd76-4bfa-8368-034f9e6657ec" />
</bp:TemplateReaction>

<bp:SmallMolecule rdf:about="57f08854-e654-48ed-afe2-2e8fcf64f344">
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">Cirmtuzumab</bp:displayName>
 <bp:entityReference rdf:resource="6c01247e-d58b-4f3e-99ed-5a10607cfd5c" />
</bp:SmallMolecule>

<bp:UnificationXref rdf:about="e21b8a18-5887-472e-80b6-03c0fccbf90a">
 <bp:id rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">9606</bp:id>
 <bp:db rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">taxonomy</bp:db>
</bp:UnificationXref>

<bp:Protein rdf:about="7de0a2db-bd76-4bfa-8368-034f9e6657ec">
 <bp:displayName rdf:datatype = "http://www.w3.org/2001/XMLSchema#string">NQO1</bp:displayName>
 <bp:entityReference rdf:resource="1ebbe45a-1207-435c-a38e-251a92e2dda9" />
</bp:Protein>
</rdf:RDF>